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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ea775e4f01873aa6f5be135a2af095ab4b27d863dbfd324c9f2f157ce562980' 
  AND token = 'i8niC3W5cCckABEfAvp8YIuiovlcS2YsDeW8yQ/cZM0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}