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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae8b62263cdb65f63cdeeb34f5e579531b5f2c92202b59b5febd50e799bd43eb' 
  AND token = 'e6VmJdig/N6vUOv2vSKhdLgUYTkZ6dtKXMRA8DNnMlg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}