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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b7faa89f47f447321a0d034ee23b53a2cac33e48b63a7093d54428d9c5b666f1' 
  AND token = 'FCvpcqNoPAPK2bkOQe4xEyRMj+sXTA37Y0ttZUphRRs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}