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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d03b81de5aa8ebd61b3ff485f974319d6aff0106d9a304e80728de1e957965a' 
  AND token = 'rLdQ2R2HJXwoBfN5pk3zAl+lzFaChL2BQdLyuVi8WD4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}