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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd16246edcc00e67ea950e97b52b92bd9b40336fe79d1c4070d6cde747e26e556' 
  AND token = '5QxRZE2SW/YPiSzOpKkANMnQpyF7pSFHitEThDoPnQ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}