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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f16f99f4430819b58cd31cd59ac4842be7eea603cb0006f2d8e5575fc2c8bc8' 
  AND token = 'sThH/TfiOY3OeQJth6h94Jvdvhqm3VJCmqN8Cf4i5Xk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}