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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f21e81f5f578dd10dc7fe42ad143a91f0f8578c6e0d56190273e1be883b53fcb' 
  AND token = 'htUKiW5J+getJV+Km10S313G7FpkIjb1VeaqWktNvGA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}