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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5a6b02d569ec69e7855e095e4546733e351c15b70cd81f65068979a63b39f5e' 
  AND token = 'z0HUW7oc5AqESUDEYUI1VSioSyukqN3M6gy5eMWiX3M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}