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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5129925afed88f8d026d2d283f6a3778ffc87e80904960e710a9b520ec0e9fd' 
  AND token = 'wbzb22PuMgfDrJE8OAAVkXhN+i/DXXetZsE/P0X2Ho4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}