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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '456491f44afff5f91fb921b9eb8da8fc4ad6aa730624543dd4e4a531cec2c3f7' 
  AND token = 'EALCkIkK3sjPdjjk8Vs8/EWrdBcQldJm+OaEEMhJd7U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}