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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed1408fb7581213fba6ea636df0c685add78b47b7dd652dbf85d01d22ce90303' 
  AND token = '46MnOcAXHkS3QWvE+tKzu+6yP5mmB6hyg7EGwggyo3I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}