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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6460390bde32c5fbd8dd477ff42d032ccf280b72863cafe8ae00183df035e46a' 
  AND token = '4EN3gNZwTJkZTRHIvM0XMkIIeZrP1LSVtqs1S6yca1o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}