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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '310e25eacead646fa2b086907833059c0b8b91730cce20ad007075b59be80d63' 
  AND token = '1Lsa2Ex9xWJF7mEdlfmkaihDCW8kZuCSBxO1L8R+8rc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}