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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '20e40493c62deb6b0e4d2f63fc927a620e8363caf28595cc25b2a55047adf29d' 
  AND token = 'sZRJAfCOvevOeHFt0htkZ6jlnFR/k/43aNDvmczsuLY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}