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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'edcd5b3af2eeb729f15512f0bd08ff68d50691e324227563acba68aa33097f0d' 
  AND token = 'ncDynzkhKSthmwVFCmVWXtqSU11q2t3ZaUAhkXGlScY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}