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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '408a22160265f498023d7188e0af8b08c7fb169f1b8d4740ed63721dc281539f' 
  AND token = 'TtsDc8m7Ozdo7WWaUqW8RitZW5JwWlnjlvOJDCj1AdQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}