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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '134daf9835ef4cd814d201cd2968b493778e7cd2dfa2457c74827065e566a226' 
  AND token = '1um/QmzU4r1UZX5AxIo6FyndnkMj3PCL8eoV61Yd1fs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}