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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74e0b736833535506a08eac6e51ef4fc21b9d6558c3b826ab3158396920c99c6' 
  AND token = 'UQvcwilFZfIDvzJ4JQCm6EAQFI+hS7Z6MXEq5UE88x4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}