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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed8c201f60253662a9ba2ece878287753863fbdf2f06a14bfe7d88da2045dca2' 
  AND token = 'kmjo8CWs7aS2aOKbSRiHQL6iQSrXBCNMJApsl5NGiPU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}