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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c03ca6d5d8a347f5ec638348778b17dd88f104284fb3f9aff5b27ea680aaddc' 
  AND token = 'Dxutp+l4Dyu5id8l55fKaaNE7EPjbZbNqpDB5xpR4S4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}