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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0389f183ed36d0a9c83f739a7b20baf048c9fc69d3292e2a5e21ce84ad46a958' 
  AND token = 'v8IOrvR58axN6m0MhD3Dq2XLMQ5+M7sRB2GPUPw3Q5A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}