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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c05cad5f7c6fde9a1d8fa29342acfbac45f54aa4d0726f88991195b4f7c3256d' 
  AND token = '8YU2FP6iMk/d9mJIS7FjR2DOd8wjxYMK9Li9rjfEfAk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}