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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d2ec5446e0777af2dcdc02dbfca7b76c8864b667a942d117fc2d17bb34d5262' 
  AND token = '4o5JMQvrwxmvMpS+3iMZ9lIm7w+a8SnwYnL5QqPwrAk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}