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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46b07ca55e8c232066f01edcba587dff85e8d8c2f76d33676ecc10522e4dabe1' 
  AND token = 'N/T/aZPtZ3sXN2BPTqTbDmYgsS20URGtCwTEyNtPhL0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}