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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42e858ca2860b1adf074ea45326fef89364be0f94e0eb7414b8bff62adb91635' 
  AND token = 'MMU+lCcyytRUk4Y4v3TuXZ+j3BHc1aNSEHl/lQfOfvY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}