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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33b75ce2c081fec3889e3dd6f47c568e9e46096865d226d4f78ae3e6c9aac900' 
  AND token = 'qULArrKmrYMbm2EAKtC7uOkSrud7GOKO3qZ2giuRvmE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}