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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a3ed3cbc79ef0805893e9e7093a2519be72c8cfc2cb9a6b37c5ec2d914c18326' 
  AND token = 'DQHlQc/0EyJVAkALXr2rioGdM78l4jy7TiXi3ch5TxU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}