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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '433145fd5c646f4922ca5b14ef541e09fe62a55c6c316e3b50e88524a9a21db3' 
  AND token = 'U8HtB5Fo2CXRXDUq08bq4Vz4AdiGPNCcsGiMVXRKbPo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}