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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b198d6f82d9ccc263b5bc2049635b404d23c5377415a4d61d7e2179e2b064186' 
  AND token = 'rNy1F3KjaXgec+uw9CQd3T5OxSFkjDRjKVUJolOTfOc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}