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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1fd0013e67a01a99bb493dee9dce8d40a07bfeb44128cb1c740de4296f4490c5' 
  AND token = 'UAvqNCSEla5/syYrivHWiHoLGh+FSs6hwLqn6j23ao4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}