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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c3a6b51dad31b6d91eb0370b9e31545ffef3466a28b2432e45422aa71fabf2bc' 
  AND token = 'SHn1Q10o3tCIfcKXGq5BQIg7yTTd6GWoLE79vGDeyUs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}