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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b381068cc3f0aff4f582e2c15fbae5cc9bbabe638a5107924e3ba992349fe8f' 
  AND token = 'aosPp5FBxKwK/34UaNi/4uf5nUa0Pjd+cCcct8sCffQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}