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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7933978443c32ee40eacfa9485643b33274a04946f3e026cf59c5198d0d91a2d' 
  AND token = 'X02Jpj4Ukr98iGl+XGOKdjSw2DO/7YKOSYM/7ev3t3A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}