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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'feb44c66000d8fecc5192b1b392077882adc02a3cff1da506e932b768e783c63' 
  AND token = 'YNU2KOiXLmBuvafkoR6D4E7r1fPcE5muagpYo3f7pZI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}