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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b3cc656efe2256a2a33c57419eab42377093a9552d555c81d40aa5c20c3d8bb4' 
  AND token = 'nZ9lc/1UT7NHU/VD8UCq4yDbD3nh0vxSk07iKMjR/YM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}