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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1685e4fee2942b699ff79ffc5819130b32fe90ab7018eee9f23f4a35ae98633' 
  AND token = 'fsNlyUz0h+w2XiIwl9t9ZeqYDoB6m2mn/yMY1uC66yM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}