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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ff1f08f9a33b3ec1107bd918ba5c0c69f7335449a2d45e208b57acfeedd4750' 
  AND token = 'mJD+8/zhNP/2T2U5Uu8nW294nQ4ro2kmi6l7f/l/3bw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}