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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b04f84f1a75be47074b01688326cc3e41238c9c9563ff6187f210b54c7e39644' 
  AND token = 'fjid+Ps9lnn3wiuB5mSVD+k83ObUtlUd5F2loOLGo24=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}