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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a22d7b061d14725d3fe7a6a7a5901abd40b2cb8af7c930be18ce2a3ea8778e4b' 
  AND token = 'YBKn49ymhVt+IR8SBgxT6yWoYi04zulI59fRSFXpWmA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}