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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b58a75967ea60d3d3857448535e24816954d138eecd98ed4dd4d4e597ac8cc48' 
  AND token = 'JLFz3OMWldjmxir/IlfxqK6pTRpSRM4F8/cZFceN5/g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}