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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e777988c6d032668039a8ed8c2855054c2c5e2c9e967c10e8cf72a01456ca35e' 
  AND token = 'TZGFWiz+kf8j1H/7/7UqZ+bAy+IeMa2mUjzgYUNnIEk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}