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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '806eaa45d5d2e2f44c655f8003c8010d9de752d38c1c9f3c9245d8398c8c0b5a' 
  AND token = 'oBpBWuE80Iyu1k9GMXJfhG0iZGLY2SFrFxpzwTsoOzU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}