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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a166a968cdf6fb0b157a731f8892b0260da683e0504eb01cd25463abb62ad302' 
  AND token = 'vWOfL9ENOn8NxWiBeGrcwfXYGskfER7RKPA3vE5BTPs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}