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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c40b5faac673abbf6aaaaebf19fe98019fce4c1dd207b9306d840c1b08d60f7d' 
  AND token = 'zhk5Mpl5JiIpaoFWnzAJQKzZoeYTTbiyIQucT0/cjus=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}