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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8fb311dda7aa5725c960986e433445458210c28b31bf3dbf91b688bf8b04553' 
  AND token = '6yHXp8dWD2dpeUODLYuFdn/m7khvsxU00LrHGZ9Gg5Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}