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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64189fe11ceb097da65805a6e826e75bf21130430527e2b5b86137334b25e00a' 
  AND token = 'bPKvSJl0cFsD1Scw3/Pk0iEAIGglNhx5sSMSDQyISsM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}