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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39d75d3f78ef691570e60ae5dbb3ad8b517f02dd48e53c83d0e78b1f5c212f20' 
  AND token = 'ygX1WUDuQTpJIrGVrklSaVvAiy3CmKE4dXeJzcfuVUw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}