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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28c3495899e300bd2c26bf1e0cde4b0af69922401005d8b7127bead5f7604841' 
  AND token = 'a5lQ9F0r0cDsALX9hB16a6wmEMWm9ix3RCgrbqdEjZc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}