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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c6e0e7d4841913436c8767940dbd96071e13fe060318a189f8fa236356cb9b9' 
  AND token = 'DPr3KV70H1fFTC+g193FxbwYPu/1o2tc9q7Ztk8sJ3Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}