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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a563451bc3d1c3465d6d9bab570eefb615c84a9c0d671a08eae4b65c034de745' 
  AND token = 'fdtdg8GWmyX4e4vvcnq2qxSlLic7ecK+q5RpjLIt4LE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}